Professor LIU Xing

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Associate professor

LIU Xing(刘行)

(+86) 0551-3607141

(+86) 0551-3607141

xing1017@@ustc.edu.cn
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Chemical Biology and Drug Action

刘 行 博士,女,现为中国科学技术大学生命科学学院副研究员。2004-2008年,就读于安徽大学化学化工学院化学专业。2008年9起为中国科学技术大学细胞生物学专业研究生,2014年获理学博士学位。2014年6月至2016年1月为中国科学技术大学博士后。其间,2011年12月至2012年12月及2013年7月至2013年12月赴美国Morehouse医学院从事访问学者研究。2016年2月受聘为中国科学技术大学副研究员。刘行博士的主要研究方向为细胞周期调控及化学生物学在细胞周期调控中的应用。已发表约20篇高质量的SCI论文,共被引用近100次。其中第一作者、通讯作者文章8篇,包括Nature Chemical Biology、PNAS、Journal of Molecular Cell Biology、Journal of Biological Chemistry、Scientific Reports等知名学术期刊。

Research Interests
Chemical Biology and Drug Action

Academic conferences
1. The 1st International Conference on Cellular Dynamics & Chemical Biology. Hefei, China. Nov 18~22nd, 2008
2. The 2nd International Conference on Cellular Dynamics & Chemical Biology. Hefei, China. Nov 19~21st, 2010
3. The 51st Annual meeting of the American Society. Denver, Colorado, United States. Dec. 3~7th, 2011.
4. The 52nd Annual meeting of the American Society. San Francisco, CA, United States. Dec. 15~19th, 2012.
5. The 53rd Annual meeting of the American Society. New Orleans, Louisiana, United States. Dec. 14~18th, 2013
6. The 54th Annual meeting of the American Society. Philadelphia, United States. Dec. 4~10th, 2014.
7. The 14th Chinese Biophysics Congress, Kunming, Yunnan, Nov.16~20, 2015.

Honors and awards
1. 2013, Graduate Travel Award, The 53th Annual meeting of the American Society for Cell Biology, New Orleans, Louisiana, United States. Oral presentation: "Helicobacter pylori VacA spatially rewires ACAP4 signaling in parietal cell secretion".
2. 2014 Annual Meeting Of Experimental Biology, San Diego CA. April 26-30, 2014. Poster: "Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly".
3. The 14th Chinese Biophysics Congress, Kunming, Yunnan, Nov.16~20, 2015. Oral presentation: "Super-resolution imaging reveals structural features underlying microtubule plus-end tracking in live cells".

主持和参与的各类国家科技计划项目:
国家自然科学基金青年项目《HP1α功能蛋白复合体组装的分子机制研究》2016-2018

Selected Publications (# equal contribution; * corresponding author )

  1. Mo F, Zhuang X, Liu X#, Zang J, Tian C, Teng M, Niu L, Hill DL, Dou Z, Fu C, and Yao X* . (2016). Acetylation of Aurora B by TIP60 orchestrates accurate chromosomal segregation in mitosis. Nat Chem Biol. 12(4):226-32.
  2. Dou Z#, Liu X#, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL, Yao X* . (2015). Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment. Proc Natl Acad Sci U S A. 112(33):E4546-55.
  3. Liu X#, Song Z#, Huo Y, Zhang J, Zhu T, Wang J, Zhao X, Aikhionbare F, Zhang J, Duan H, Wu J, Dou Z, Shi Y and Yao X* . (2014). HP1α interacts with borealin and specifies the centromere localization of chromosomal passenger complex. J Biol Chem. 289(30):20638-20649.
  4. Shao H, Huang Y, Zhang L, Yuan K, Chu Y, Dou Z, Jin C, Garcia-Barrio M, Liu X* , Yao X* . (2015). Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation. Sci Rep. 5:12204.
  5. Jiang H, Wang W, Zhang Y, Yao WW, Jiang J, Qin B, Yao WY, Liu F, Wu H, Ward TL, Chen CW, Liu L, Ding X* , Liu X* , Yao X* . (2015). Cell polarity kinase MST4 cooperates with cAMP-dependent kinase to orchestrate histamine-stimulated acid secretion in gastric parietal cells. J Biol Chem. 290(47):28272-85.